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Semantic Software Lab
Concordia University
Montréal, Canada

Mutation Miner

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1. Overview

The Mutation Miner project was initiated in 2004 by Christopher J.O. Baker (UNB) and René Witte.
NLP-extracted textual annotations mapped onto a protein's structure
Mutation Miner targets users for a specific area in biology: protein engineers. Information about protein mutations described in full-text research papers is extracted through a text mining subsystem and mapped to protein databases using a sophisticated pipeline of bioinformatics tools. The end result is transferred to a 3D-visualization of a particular molecule, showing information extracted from documents in a spatial context meaningful to bio-engineers. Mutation Miner was one of the first systems that goes beyond simply delivering information extracts by integrating a complete natural language subsystem into a biologically relevant application, thereby combining text analysis with bioinformatics algorithms.

2. Project Members

2.1. Project supervision

2.2. Current Group Members

Nona Naderi
Mutation Impact Analysis

2.2.1. Past Group Members

Thomas Kappler
Mutation Miner Ontology & Ontology Population
Vladislav Ryzhikov
Mutation Miner NLP Pipeline
Ashwin Bhat Gurpur
Protein Sequence Mapping

3. Further Information

A number of publications are available online.